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Biophysics

Biophysics

Tumour compression could be responsible for chemotherapy resistance

30 Sep 2020 Tami Freeman
Chemoresistance in spheroids
Unconfined spheroids (top row) grew larger and were more susceptible to drug treatment than spheroids grown under mechanical stress (bottom row). (Courtesy: Morgan Delarue)
As tumours progress and grow, they undergo mechanical alterations such as changes in extracellular m

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